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Although there are few sufficient experimental or clinical evidences about the synergy or addition effect of polysaccharides in cancer treatment, these findings certainly highlight the advantage of polysaccharides in conjunction with chemotherapy or radiotherapy, and also represent a novel strategy for addressing chemoresistance in cancer therapy

The mechanism likely involves stress reduction (lowering cortisol that suppresses BDNF) combined with attentional training that directly engages BDNF-dependent hippocampal and prefrontal circuits

doi: 10.1136/gutjnl-2021-326269 254 KesikaPSuganthyNSivamaruthiBSChaiyasutC

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